3-Chloro-5-hydroxybenzoic Acid CAS 53984-36-4

Product Description:

Product Name: 3-Chloro-5-hydroxybenzoic acid CAS NO: 53984-36-4

Synonyms:

5-Chloro-m-salicylic Acid;3-chloro-5-hydroxy BA;

Benzoic acid, 3-chloro-5-hydroxy-;

GPR81 Agonist, 3Cl-5OH-BA;

Chemical Physical Properties:

Appearance: White to beige powder

Assay : Greater than or equal to 99.0 percent

Density: 1.536 g/cm3

Boiling Point: 364.805 degree at 760 mmHg

Melting point: 244.0 to 248.0 degree

Flash Point: 174.428 degree

Storage temp.: Sealed in dry,Room Temperature

Solubility: DMSO: soluble15mg/mL (clear solution)

Safety Information:

HS Code: 2918290000

Caution Statement: P261; P280; P305 plus P351 plus P338

Signal Word: Danger

Symbol: GHS05, GHS07

Hazard Declaration: H302; H315; H318; H335

5-Chloro-m-salicylic Acid was studied as a potential selective lactate receptor (GPR81) agonists with antilipolytic effects. GPR81, also known as hydroxycarboxylic acid receptor 1 (HCAR1), is a recently de-orphanized receptor that is activated by lactic acid (EC50 1.5 mM) but not by other hydroxycarboxylic acids. 3-chloro-5-hydroxy Benzoic Acid (3-chloro-5-hydroxy BA) is an agonist of GPR81 (EC50 = 16 μM) that is inactive against the related GPR109a (HCAR2) receptor. It is similarly effective at GPR81 receptors from a variety of mammalian species and is bioavailable, stimulating lipolysis (increased serum free fatty acids) in mice fed high fat chow for 10 weeks. 3-chloro-5-hydroxy BA, like lactate, blocks basal ghrelin secretion by primary gastric mucosal cells.

If you are interested in our products or have any questions, please feel free to contact us!

Products under patent are offered for R D purpose only. However, the final responsibility lies exclusively with the buyer.

ڈاؤن لوڈ، اتارنا ٹیگ: 3-chloro-5-hydroxybenzoic acid cas 53984-36-4, manufacturers, suppliers, factory, buy, in stock

• کا ایک جوڑا: 3-Chloro-5-hydroxybenzoic Acid Methyl Ester CAS 98406-04-3
• اگلا: گلوٹارک انہائیڈرائڈ سی اے ایس 108-55-4